An elite team of soldiers thwart the evil Cobra organization's desire for world domination at every turn, cleverly stopping them from controlling the weather, creating unstoppable weapons, and genetically engineering super-warriors.
Ted Harrison
Duke (voice)

Christopher Collins
Cobra Commander (voice)

Maurice LaMarche
Destro (voice)

Don Brown
Sub-Zero (voice)

Garry Chalk
Pathfinder (voice)

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Cobra attempts to cripple the Joes from within by replacing leaders and committee members with artificial beings known as synthoids. The synthoids cut G. I. Joe's budget and eventually order the team to disband.
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Cobra seizes control of a new satellite for use with a new transportation device, and Duke is captured in the attempt. The G.I. Joe team learns that they must build their own device to defeat Cobra.